Products

    Enfamil® Premature 24 Cal/fl oz HP

    Milk-based infant formula with extra protein for premature or low birth weight infants who are not breastfed

    Indication

    Enfamil Premature 24 Cal/fl oz High Protein (HP) is a milk-based infant formula specifically formulated to meet the unique nutritional needs of rapidly growing premature or low birth weight infants who do not receive human milk.* The Enfamil Premature Nutrition portfolio is the only premature infant formula line designed to meet the latest Global Expert Recommendations for all labeled nutrients. Protein is a major driver of lean mass growth and neuro-cognitive outcomes, and Enfamil Premature Nutrition supports these protein needs.

    Additional Usage Guidelines

    When more than 12 fl oz (355 mL) of 24 Calories/fl oz product is used per day, which may occur in larger infants weighing over 2500 g (5.5 lbs) consuming only Enfamil Premature, intake of some nutrients (eg, fat soluble vitamins) may be excessive. In such circumstances, it should be used only at the direction and under the supervision of a doctor. Enfamil® NeuroPro EnfaCare® may be a product to consider in such circumstances.

    *Increased caloric density, protein, and some vitamins and minerals compared to standard term formula to help support weight and growth in babies born prematurely.

    Ingredients

    Ingredients: Ready To Feed (2 fl oz Nursette bottles): Water, nonfat milk, corn syrup solids, whey protein concentrate, lactose, medium chain triglycerides (MCT oil), soy oil, high oleic sunflower oil and less than 0.5%: Mortierella alpina oil*, Crypthecodinium cohnii oil, calcium phosphate, calcium hydroxide, potassium citrate, sodium chloride, calcium carbonate, magnesium phosphate, calcium chloride, sodium citrate, ferrous sulfate, zinc sulfate, cupric sulfate, potassium iodide, sodium selenite, sodium ascorbate, vitamin E acetate, niacinamide, calcium pantothenate, vitamin A palmitate, vitamin D3, thiamin hydrochloride, riboflavin, vitamin B6 hydrochloride, folic acid, vitamin K1, biotin, vitamin B12, rice starch, inositol, mono- and diglycerides, soy lecithin, choline chloride, nucleotides (cytidine 5’-monophosphate, adenosine 5’-monophosphate, disodium uridine 5’-monophosphate, disodium guanosine 5’-monophosphate), taurine, L-carnitine.

    *A source of arachidonic acid (ARA).
    †A source of docosahexaenoic acid (DHA).

    POTENTIAL ALLERGENS

    Enfamil Premature 24 Cal HP contains milk and soy.

    Nutrients

    (Normal Dilution)

    Per 100 Calories

    Per 100 mL

    Protein, g

    3.6

    2.9

    Fat, g

    5

    4.1

    Linoleic acid, mg

    810

    660

    Carbohydrate, g

    10.5

    8.5

    Water, g

    108

    88

    Vitamins/Other Nutrients

       

    Vitamin A, IU

    1350

    1100

    Vitamin D, IU

    300

    240

    Vitamin E, IU

    6.3

    5.1

    Vitamin K, mcg

    9

    7.3

    Thiamin (Vitamin B1), mcg

    200

    162

    Riboflavin (Vitamin B2), mcg

    300

    240

    Vitamin B6, mcg

    150

    122

    Vitamin B12, mcg

    0.25

    0.2

    Niacin, mcg

    4000

    3200

    Folic acid (Folacin), mcg

    40

    32

    Pantothenic acid, mcg

    1200

    970

    Biotin, mcg

    4

    3.2

    Vitamin C (Ascorbic acid), mg

    20

    16.2

    Choline, mg

    24

    19.5

    Inositol, mg

    44

    36

    Minerals

       

    Calcium, mg

    165

    134

    Phosphorus, mg

    90

    73

    Magnesium, mg

    9

    7.3

    Iron, mg

    1.8

    1.46

    Zinc, mg

    1.5

    1.22

    Manganese, mcg

    6.3

    5.1

    Copper, mcg

    120

    97

    Iodine, mcg

    25

    20

    Selenium, mcg

    5

    4.1

    Sodium, mg

    70

    57

    Potassium, mg

    98

    80

    Chloride, mg

    106

    86

    Product nutrient values and ingredients are subject to change. Please see product label for current information.

    Nutrient Density

    24 Calories/fl oz

    Protein (% Calories)

    14

    Whey:Casein Ratio

    80:20

    Fat (% Calories)

    44

    Carbohydrate (% Calories)

    42

    Potential Renal Solute Load (mOsm/100 Calories)9

    32

    Potential Renal Solute Load (mOsm/100 mL)9

    26

    Osmolality (mOsm/kg water)

    300

    Osmolarity (mOsm/L)

    260

    Lactose-free

    No

    AMINO ACID COMPOSITION

    ESSENTIAL AMINO ACIDS

     

    mg/100 Cal

    mg/100 mL Liq

    Histidine

    83

    67

    Isoleucine

    220

    177

    Leucine

    400

    320

    Lysine

    330

    270

    Methionine

    79

    64

    Cysteine

    83

    67

    Phenylalanine

    137

    110

    Tyrosine

    126

    102

    Threonine

    250

    200

    Tryptophan

    69

    56

    Valine

    220

    177

    NONESSENTIAL AMINO ACIDS

     

    mg/100 Cal

    mg/100 mL Liq

    Arginine

    101

    81

    Alanine

    176

    142

    Aspartic Acid

    390

    310

    Glutamic Acid

    700

    560

    Glycine

    72

    58

    Proline

    260

    210

    Serine

    210

    165

    Product Forms and Ordering Information

    ENFAMIL® PREMATURE 24 Cal/fl oz HP IS AVAILABLE IN READY-TO-USE NURSETTE® BOTTLES

    When using this information, please note the following:

     

    Coding systems and reimbursement allowable rates vary by payer:

    • Medicare Part B uses HCPCS (Healthcare Common Procedure Coding System) to group products
    • Medicaid systems vary by state; some use HCPCS while others use NDC format code or systems of their own—contact your state provider for more information
    • Private health insurance and managed care companies may use HCPCS, NDC format code or their own system—contact your provider for more information

    Enfamil® Premature 24 Cal/fl oz HP, Ready-to-Feed
    Item #: 156601
    Description: RTF, 24 Cal/fl oz
    Unit Size: 2 fl oz bottle
    Calories/Unit: 48
    Product Yield/Unit (fl oz): 2
    Case: 48 bottles per case
    HCPCS Code: B4160
    NDC Format Code: 00087-5115-74

    PRODUCT BENEFITS

    Enfamil Premature 24 Cal/fl oz HP is specifically formulated to meet the unique nutritional needs of rapidly growing premature or low birth weight infants

    • 6 g of protein/100 Calories—appropriate for growth and development1-3
    • Fat blend is 40% medium-chain triglycerides (MCT) oil to promote fat absorption4,5
    • Carbohydrate blend of 60% corn syrup solids (glucose polymers) and 40% lactose that is easily digested and helps avoid overloading the premature infant's capacity to digest lactose
    • Provides approximately 2 mg iron/kg body weight when fed at 120 Cal/kg body weight per day
    • 80:20 whey-to-casein ratio patterned after early human milk*

    In a multi-center study, 64% of preterm infants had low vitamin Dconcentrations at birth6

    Meets the 2014 Global Expert Recommendations for all labeled nutrients, including vitamin D1

    • Calcium, phosphorus and vitamin D within the ranges recommended by experts to help support bone mineralization and growth1:
    • Calcium: phosphorus ratio = 1.83:1
    • DHA at 0.34% of total fatty acids, similar to the worldwide breast milk average‡7, to help support brain and eye development and to help support blood DHA concentration8

    Additional product features:

    • Kosher, Halal

    *Whey-to-casein ratio 3-5 days after lactation begins.
    †Serum 25 (OH) D concentrations <50 nmol/L at birth.
    ‡Average amount of DHA in worldwide breast milk is 0.32% ± 0.22% (mean ± standard deviation of total fatty acids) based on

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    References

    1. Koletzko B, Poindexter B, Uauy R (eds). Nutritional Care of Preterm Infants: Scientific Basis and Practice Guidelines. World Rev Nutr Diet.Basel, Karger, 2014; 110:1-314.
    2. Klein CJ. Nutrient requirements for preterm infant formulas. J Nutr.2002;132(suppl):1395S-1577S.
    3. Agostoni C, Buonocore G, Carnielli VP, et al. Enteral nutrient supply for preterm infants: commentary from the European Society of Paediatric Gastroenterology, Hepatology and Nutrition Committee on Nutrition. J Pediatr Gastroenterol Nutr.2010;50:85-91.
    4. Tantibhedhyangkul P, Hashim SA. Medium-chain triglyceride feeding in premature infants: effects on fat and nitrogen absorption. 1975;55:359-370.
    5. Andrews BF, Lorch V. Improved fat and Ca absorption in LBW infants fed a medium-chain triglyceride containing formula [abstract]. Pediatr Res.1974;8:104.
    6. Monangi N et al. Vitamin D status of early preterm infants and the effects of vitamin D intake during hospital stay Arch Dis Child Fetal Neonatal Ed.2014;99:F166-F168.
    7. Brenna JT, Varamini B, Jensen RG, et al. Docosahexaenoic and arachidonic acid concentrations in human breast milk worldwide. Am J Clin Nutr.2007;85:1457-1464.
    8. Innis SM, Adamkin DH, Hall RT, et al. Docosahexaenoic acid and arachidonic acid enhance growth with no adverse effects in preterm infants fed formula. J Pediatr.2002;140:547-554.
    9. Fomon SJ, Ziegler EE. Renal solute load and potential renal solute load in infancy. J Pediatr. 1999;134:11-14.