Enfamil® ProSobee®
Plant-based formula with plant-sourced protein, designed to reduce fussiness and gas caused by sensitivity to milk-based formulas.
Enfamil ProSobee is a 20 Cal/fl oz soy-based formula for the routine feeding of infants with feeding issues resulting from sensitivity to milk-based formula. Enfamil ProSobee is for babies with sensitive tummies when a soy formula is preferred. Enfamil ProSobee is lactose-free.
Enfamil ProSobee is a soy-based infant formula clinically shown to reduce fussiness and gas within 24 hours*1
- Plant-sourced protein that is naturally easy on baby’s tummy
- Milk-free and suitable for infants with lactose intolerance
- Dairy-free for when parents want to avoid cow’s milk in their baby’s diet
DHA is:
- Clinically proven† to support mental, visual and immune system development3–6
- Clinically shown to improve long-term cognitive outcomes through 5 years of age†7
- Shown to improve respiratory health through the first 3 years of life when infants were fed through 12 months†3
Additional product features:
- Lactose-free
- No artificial flavors, sweeteners or colors
- Kosher Dairy (OU-D), Halal
*Vs. the same infants at the beginning of the study.
†Studies compared infants fed Enfamil with DHA and ARA vs. discontinued Enfamil without DHA and ARA; studied before the addition of prebiotics.
‡Average amount of DHA in worldwide breast milk is 0.32% ± 0.22% (mean ± standard deviation of total fatty acids) based on an analysis of 65 studies of 2,474 women.
Enfamil ProSobee is designed to provide a sole source of nutrition for infants up to age 6 months and provide a major source of nutrition through 12 months of age when indicated.
Ingredients: Powder: Corn syrup solids (54%), vegetable oil (26%) (palm olein, coconut, soy and high oleic sunflower oils), soy protein isolate (14%) and less than 2%: calcium phosphate, potassium chloride, sodium citrate, calcium carbonate, magnesium chloride, magnesium phosphate, potassium citrate, ferrous sulfate, zinc sulfate, cupric sulfate, potassium iodide, sodium selenite, Mortierella alpina oil*, Crypthecodinium cohnii oil†, L-methionine, choline chloride, ascorbic acid, niacinamide, calcium pantothenate, vitamin D3, riboflavin, thiamin hydrochloride, vitamin B6 hydrochloride, folic acid, vitamin K1, biotin, vitamin B12, inositol, taurine, vitamin E acetate, L-carnitine, vitamin A palmitate
Ingredients: Ready-to-Use (2 fl oz Nursette bottle): Water (87%), corn syrup solids (7%), vegetable oil (palm olein, soy, coconut and high oleic sunflower oils) (3%), soy protein isolate (2%) and less than 1%: Mortierella alpina oil*, Crypthecodinium cohnii oil†, calcium phosphate, potassium citrate, calcium carbonate, sodium chloride, magnesium chloride, magnesium phosphate, potassium chloride, ferrous sulfate, zinc sulfate, cupric sulfate, potassium iodide, sodium selenite, soy lecithin, ascorbic acid, vitamin E acetate, niacinamide, calcium pantothenate, vitamin A palmitate, vitamin B12, vitamin D3, thiamin hydrochloride, riboflavin, vitamin B6 hydrochloride, folic acid, vitamin K1, biotin, mono- and diglycerides, L-methionine, choline chloride, carrageenan, inositol, taurine, L-carnitine.
Ingredients: Ready To Use (32 fl oz bottle): Water (87%), corn syrup solids (7%), vegetable oil (palm olein, soy, coconut and high oleic sunflower oils) (3%), soy protein isolate (2%) and less than 2%: Mortierella alpina oil*, schizochytrium sp. oil†, calcium phosphate, potassium citrate, sodium chloride, calcium carbonate, magnesium phosphate, potassium chloride, ferrous sulfate, zinc sulfate, cupric sulfate, potassium iodide, manganese sulfate, sodium selenite, soy lecithin, sodium ascorbate, vitamin E acetate, ascorbic acid, niacinamide, calcium pantothenate, vitamin A palmitate, thiamin hydrochloride, riboflavin, vitamin B6 hydrochloride, folic acid, vitamin K1, biotin, vitamin B12, vitamin D3, mono- and diglycerides, carrageenan, choline chloride, inositol, L-methionine, taurine, L-carnitine.
Ingredients: Concentrate (13 fl oz can): Water (75%), corn syrup solids (14%), vegetable oil (palm olein, soy, coconut and high oleic sunflower oils) (6%), soy protein isolate (4%) and less than 1%: Mortierella alpina oil*, Crypthecodinium cohnii oil†, mono- and diglycerides, soy lecithin, carrageenan, vitamin A palmitate, vitamin D3, vitamin E acetate, vitamin K1, thiamin hydrochloride, riboflavin, vitamin B6 hydrochloride, vitamin B12, niacinamide, folic acid, calcium pantothenate, biotin, ascorbic acid, choline chloride, inositol, calcium carbonate, calcium phosphate, magnesium chloride, magnesium phosphate, ferrous sulfate, zinc sulfate, cupric sulfate, potassium iodide, sodium selenite, sodium chloride, potassium citrate, potassium chloride, L-methionine, taurine, L-carnitine.
*A source of arachidonic acid (ARA).
†A source of docosahexaenoic acid (DHA).
POTENTIAL ALLERGENS
Enfamil ProSobee contains soy.
Ingredient Transparency
Explore the function behind our ingredients.
| (Normal Dilution) | Per 100 Cal (5 fl oz) | Per 100 mL | Per 100 grams Pwd (510 Cal) |
|---|---|---|---|
| Protein, g | 2.5 | 1.69 | 12.7 |
| Fat, g | 5.3 | 3.6 | 27 |
| Linoleic acid, mg | 800- Pwd 860- Liquid | 540- Pwd 580- Liquid | 4100 |
| Carbohydrate, g | 10.6 | 7.2 | 54 |
| Water, g | 133- Pwd and 2 fl oz RTU 134- Conc and 8 fl oz RTU | 90- Pwd and 2 fl oz RTU 91- Conc and 8 fl oz RTU | 2.6 |
| Vitamins/Other Nutrients | |||
| Vitamin A, IU | 300 | 200 | 1530 |
| Vitamin D, IU | 60 | 41 | 310 |
| Vitamin E, IU | 2 | 1.35 | 10.2 |
| Vitamin K, mcg | 9 | 6.1 | 46 |
| Thiamin (Vitamin B1), mcg | 80 | 54 | 410 |
| Riboflavin (Vitamin B2) mcg | 90 | 61 | 460 |
| Vitamin B6, mcg | 60 | 41 | 310 |
| Vitamin B12, mcg | 0.3 | 0.2 | 1.53 |
| Niacin, mcg | 1000 | 680 | 5100 |
| Folic acid (Folacin), mcg | 16 | 10.8 | 81 |
| Pantothenic acid, mcg | 500 | 340 | 2500 |
| Biotin, mcg | 3 | 2 | 15.3 |
| Vitamin C (Ascorbic acid), mg | 12 | 8.1 | 61 |
| Choline, mg | 24 | 16.2 | 122 |
| Inositol, mg | 6 | 4.1 | 31 |
| Minerals | |||
| Calcium, mg | 105 | 71 | 530 |
| Phosphorus, mg | 69 | 47 | 350 |
| Magnesium, mg | 8 | 5.4 | 41 |
| Iron, mg | 1.8 | 1.22 | 9.2 |
| Zinc, mg | 1.2 | 0.81 | 6.1 |
| Manganese, mcg | 25 | 16.9 | 127 |
| Copper, mcg | 75 | 51 | 380 |
| Iodine, mcg | 15 | 10.1 | 76 |
| Selenium, mcg | 2.8 | 1.89 | 14.2 |
| Sodium, mg | 36 | 24 | 183 |
| Potassium, mg | 120 | 81 | 610 |
| Chloride, mg | 80 | 54 | 410 |
Product nutrient values and ingredients are subject to change. Please see product label for current information.
| Nutrient Density | 20 Calories/fl oz |
|---|---|
| Protein (% Calories) | 10 |
| Fat (% Calories) | 48 |
| Carbohydrate (% Calories) | 42 |
| Potential Renal Solute Load (mOsm/100 Calories)4 | 23 |
| Potential Renal Solute Load (mOsm/100 mL)4 | 15.6 |
| Osmolality (mOsm/kg water) | 200 (2 fl oz) 178 (Pwd) 170 (8 fl oz RTU, 13 fl oz Conc) |
| Osmolarity (mOsm/L) | 180 (2 fl oz) 160 (Pwd) 155 (8 fl oz RTU, 13 fl oz Conc) |
| Lactose-free | Yes |
Supplemented with L-methionine
ǂAt 20 Cal/fl oz
Source of protein: 100% Soy protein isolate
DILUTION INFORMATION FOR ENFAMIL PROSOBEE
Mixing instruction by the scoop
Download dilution information ↗
Mixing instruction by the quart
Download dilution information ↗
POWDER
A baby’s health depends on carefully following the instructions below. Use as directed by a medical professional. Proper hygiene, preparation, dilution, use and storage are important when preparing infant formula. Powdered infant formulas are not sterile and should NOT be fed to premature infants or infants who might have immune problems unless directed and supervised by a doctor. Discuss with parents which formula is appropriate for the baby.
Discuss with parents whether they need to use cooled, boiled water for mixing and whether they need to boil clean utensils, bottles and nipples in water before use.
WARNING: Do not use a microwave oven to warm formula. Serious burns may result.
Refer to the product label for the most accurate information.
Failure to follow these instructions could result in severe harm. Once prepared, infant formula can spoil quickly. Either feed immediately or cover and store in refrigerator at 35–40°F (2–4°C) for no longer than 24 hours. Do not use prepared formula if it is unrefrigerated for more than a total of 2 hours. Do not freeze prepared formula. After feeding begins, use formula within 1 hour or discard.
Wash hands thoroughly with soap and water before preparing formula. Pour the desired amount of water into the bottle. Add powder. Cap bottle and SHAKE WELL.
Use the following chart for correct amounts of water and powder. Use scoop in can to measure powder.
Store DRY scoop in lid holder in tub or in can.
| To Make* | Water | Powder | Weight |
|---|---|---|---|
| 2 fl oz bottle | 2 fl oz | 1 unpacked level scoop | 8.8 g |
| 4 fl oz bottle | 4 fl oz | 2 unpacked level scoops | 17.6 g |
| 8 fl oz bottle | 8 fl oz | 4 unpacked level scoops | 35.2 g |
*Each scoop adds about 0.2 fl oz to the amount of prepared formula.
Powder Storage: Store cans at room temperature. After opening can, keep tightly covered, store in a dry area and use contents within 1 month. Do not freeze powder and avoid excessive heat. Use by date on bottom of can.
READY-TO-FEED
2 fl oz Nursette® Bottles
Instructions for Use
A baby’s health depends on carefully following the instructions below. Proper hygiene, preparation, use and storage are important when preparing infant formula. Use as directed by the baby’s doctor. Discuss with parents whether they need to boil a clean nipple in water before use. Inspect each bottle for signs of damage.
2 fl oz Nursette Bottles
Wash hands thoroughly with soap and water before preparing bottle for feeding.
SHAKE BOTTLE WELL and remove cap.
Attach nipple unit (not included).
WARNING: Do not use a microwave oven to warm formula. Serious burns may result.
Failure to follow these instructions could result in severe harm. Opened bottles can spoil quickly. Either feed immediately or replace cap and store in refrigerator at 35–40°F (2–4°C) for no longer than 24 hours. Do not use opened bottle if it is unrefrigerated for more than a total of 2 hours. Do not freeze. After feeding begins, use formula within 1 hour or discard.
Storage: Store unopened bottles at room temperature. Avoid excessive heat and prolonged exposure to light.
DO NOT ACCEPT IF PACKAGE HAS BEEN OPENED.
DO NOT USE IF CAP RING IS BROKEN OR MISSING.
USE BY DATE ON CARTON AND BOTTLE LABEL.
32 fl oz Bottle
A baby’s health depends on carefully following the instructions below. Use as directed by a medical professional. Proper hygiene, preparation, use and storage are important when preparing infant formula. Discuss with parents which formula is appropriate for the baby.
32 fl oz Bottle
Wash hands thoroughly with soap and water before preparing feeding bottles. SHAKE BOTTLE WELL, remove protective seal around cap, remove cap and foil seal. Replace cap. Pour into feeding bottle(s).
WARNING: Do not use a microwave oven to warm formula. Serious burns may result.
Failure to follow these instructions could result in severe harm. Opened bottles and prepared formula can spoil quickly. Either feed immediately or cover and store in refrigerator at 35–40°F (2–4°C) for no longer than 48 hours. Do not use opened bottle and/or prepared formula if they are unrefrigerated for more than a total of 2 hours. Do not freeze prepared formula. After feeding begins, use prepared formula within 1 hour or discard.
Storage: Store unopened bottle at room temperature. Avoid excessive heat. Do not freeze. Use by date on side of bottle. Do not use if protective seal around cap, or if foil seal under cap, is damaged or missing.
CONCENTRATE
A baby’s health depends on carefully following the instructions below. Use only as directed by a medical professional. Proper hygiene, preparation, dilution, use and storage are important when preparing infant formula. Discuss with parents which formula is appropriate for the baby.
13 fl oz Cans
Wash hands thoroughly with soap and water before preparing formula.
Clean can lid, SHAKE CAN WELL and open.
Pour desired amount of water into the bottle. Add an equal amount of concentrated liquid. Shake or stir well.
WARNING: Do not use a microwave oven to warm formula. Serious burns may result.
Failure to follow these instructions could result in severe harm. Opened cans and prepared formula can spoil quickly. Either feed immediately or cover and store in refrigerator at 35–40°F (2–4°C) for no longer than 48 hours. Do not use opened can and/or prepared formula if they are unrefrigerated for more than a total of 2 hours. Do not freeze prepared formula. After feeding begins, use prepared formula within 1 hour or discard.
Storage: Store unopened cans at room temperature. Avoid excessive heat. Do not freeze.
Use by date on top of can.
ENFAMIL PROSOBEE IS AVAILABLE IN POWDER, READY-TO-FEED LIQUID, AND CONCENTRATE
Coding systems and reimbursement allowable rates vary by payer:
- Medicare Part B uses HCPCS (Healthcare Common Procedure Coding System) to group products
- Medicaid systems vary by state; some use HCPCS while others use NDC format code or systems of their own—contact your state provider for more information
- Private health insurance and managed care companies may use HCPCS, NDC format code or their own system—contact your provider for more information

Enfamil® ProSobee®, Concentrate
Item #: 119501
Description: Concentrate
Unit Size: 13 fl oz can
Calories/Unit: 520
Product Yield/Unit (fl oz): 26
Case: 12 cans per case
HCPCS Code: B4159
NDC Format Code: 00087-1195-41

Enfamil® ProSobee®, Powder (12.9 oz can)
Item #: 121401
Description: Powder
Unit Size: 12.9 oz can
Calories/Unit: 1860
Product Yield/Unit (fl oz): 93
Case: 6 cans per case
HCPCS Code: B4159
NDC Format Code: 00087-1214-41

Enfamil® ProSobee®, Powder (20.9 oz can)
Item #: 121483
Description: Powder
Unit Size: 20.9 oz can
Calories/Unit: 3000
Product Yield/Unit (fl oz): 150
Case: 4 cans per case
HCPCS Code: B4159
NDC Format Code: 00087-1214-42

Enfamil® ProSobee®, Ready-to-Feed (2 fl oz Nursette® bottle)
Item #: 144901
Description: RTF
Unit Size: 2 fl oz bottle
Calories/Unit: 40
Product Yield/Unit (fl oz): 2
Case: 48 bottles per case
HCPCS Code: B4159
NDC Format Code: 00087-1449-41

Enfamil® ProSobee®, Ready-to-Feed (32 fl oz bottle)
Item #: 184101
Description: RTF
Unit Size: 32 fl oz bottle
Calories/Unit: 640
Product Yield/Unit (fl oz): 32
HCPCS Code: B4159
NDC Format Code: 00087-5123-64
- Berseth CL, Johnston WH, Stolz SI, et al. Clinical response to 2 commonly used switch formulas occurs within 1 day. Clin Pediatr (Phila). 2009;48:58-65.
- Brenna JT, Varamini B, Jensen RG, et al. Docosahexaenoic and arachidonic acid concentrations in human breast milk worldwide. Am J Clin Nutr. 2007;85:1457-1464.
- Birch EE, Khoury JC, Berseth CL, et al. The impact of early nutrition on incidence of allergic manifestations and common respiratory illnesses in children. J Pediatr. 2010;156:902-906.
- Birch EE, Hoffman DR, Uauy R, et al. Visual acuity and the essentiality of docosahexaenoic acid and arachidonic acid in the diet of term infants. Pediatr Res. 1998;44:201-209.
- Birch EE, Garfield S, Hoffman DR, et al. A randomized controlled trial of early dietary supply of long-chain polyunsaturated fatty acids and mental development in term infants. Dev Med Child Neurol. 2000;42:174-181.
- Morale SE, Hoffman DR, Castaneda YS, et al. Duration of long-chain polyunsaturated fatty acids availability in the diet and visual acuity. Early Hum Dev. 2005;81:197-203.
- Colombo J, Carlson SE, Cheatham CL, et al. Long-term effects of LCPUFA supplementation on childhood cognitive outcomes. Am J Clin Nutr. 2013;98:403-412.
- Fomon SJ, Ziegler EE. Renal solute load and potential renal solute load in infancy. J Pediatr. 1999;134:11-14.
